Eivind Wang

Professor Eivind Wang is a distinguished figure in the field of medicine, with a particular focus on physiology, aging, neuroscience, skeletal muscle, exercise medicine, endurance training, and strength training. His extensive background and wealth of knowledge make him a vital contributor to our services.

Contributions and Research

Professor Wang earned his Ph.D. in Clinical Medicine from the Faculty of Medicine at the Norwegian University of Science and Technology (NTNU).Professor Wang's research has significantly advanced our understanding of the 4x4 strength and endurance principle.

His career includes current and past positions at the Exercise Training Clinic, Department of Østmarka, Division of Mental Health Care, St. Olavs University Hospital in Trondheim, Norway; the Department of Circulation and Medical Imaging, Faculty of Medicine at NTNU, Trondheim, Norway; and the Department of Internal Medicine, Division of Geriatrics at the Faculty of Medicine, University of Utah, USA.

Cardiac Physiology

Stroke volume response during prolonged exercise depends on left ventricular filling: evidence from a β-blockade study.

Laginestra FG, Berg OK, Nyberg SK, Venturelli M, Wang E, Helgerud JAm J Physiol Regul Integr Comp Physiol · 2023DOI: 10.1152/ajpregu.00293.2022PMID: 37306400

Thirteen healthy young men completed prolonged cycling exercise with and without β1-blockade. Preventing heart-rate drift increased end-diastolic volume and stroke volume, supporting the conclusion that stroke-volume regulation during prolonged exercise is closely linked to left ventricular filling time and loading conditions.

View paper Strength Training

Maximal strength training: the impact of eccentric overload.

Tøien T, Pedersen Haglo H, Unhjem R, Hoff J, Wang EJ Neurophysiol · 2018DOI: 10.1152/jn.00609.2018PMID: 30332319

The study compared maximal strength training with and without eccentric overload to determine whether overload before the concentric phase would enhance neuromuscular adaptations. Eccentric overload did not further improve efferent neural drive or force-generating capacity, suggesting that high-intensity concentric loading may already provide near-maximal neuromuscular stimulus.

View paper Inflammatory Rheumatic Disease

Maximal strength training in patients with inflammatory rheumatic disease: implications for physical function and quality of life.

Haglo H, Berg OK, Hoff J, Helgerud J, Wang EEur J Appl Physiol · 2022DOI: 10.1007/s00421-022-04948-wPMID: 35438424

Patients with inflammatory rheumatic disease were randomized to maximal strength training or a control group. The training group showed high session attendance and protocol compliance, increased one-repetition maximum and rate of force development, and improved health-related quality-of-life dimensions, indicating that maximal strength training was well tolerated and clinically relevant.

View paper Body Composition

Abdominal aerobic endurance exercise reveals spot reduction exists: A randomized controlled trial.

Brobakken MF, Krogsaeter I, Helgerud J, Wang E, Hoff JPhysiol Rep · 2023DOI: 10.14814/phy2.15853PMID: 38010201

Overweight men were randomized to abdominal endurance exercise combined with treadmill running or treadmill running alone, with energy expenditure closely matched between groups. The results suggested that targeted abdominal endurance work combined with aerobic exercise can produce greater abdominal fat reduction than aerobic exercise alone.

View paper HIIT and VO₂max

Aerobic high-intensity intervals improve V̇O2max more than supramaximal sprint intervals in females, similar to males.

Helgerud J, Hov H, Mehus H, Balto B, Boye A, Finsås L, Hoff J, Wang EScand J Med Sci Sports · 2023DOI: 10.1111/sms.14470PMID: 37608507

The study compared aerobic high-intensity interval training with supramaximal sprint interval training in females, motivated by prior evidence in males and possible sex-dependent training responses. Aerobic high-intensity intervals improved VO₂max more than sprint intervals, supporting 4x4-style aerobic intervals as an effective method for increasing maximal oxygen uptake.

View paper Severe Mental Disorders

Physical Health Impairment and Exercise as Medicine in Severe Mental Disorders: A Narrative Review.

Brobakken MF, Nygård M, Wang ESports Med Open · 2022DOI: 10.1186/s40798-022-00490-3PMID: 36107334

This narrative review evaluated physical health impairment in severe mental disorders, including schizophrenia spectrum disorders, bipolar disorder, and major depressive disorder. It concluded that reduced aerobic endurance and skeletal muscle strength are clinically important, and that structured physical training should be included in clinical practice to counteract impaired physical health.

View paper